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GSK3685032 TFA Chemical Structure

GSK3685032 TFA

Data Sheet For research use only. Not for human use.
Cat. No. :BCP45843CAS No. :GSK3685032TFAPurity:98%
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  • Chemical Properties&Biological Activity
CAS No. GSK3685032TFA Cat. No. BCP45843
Related Products 2170137-61-6(GSK 3685032) 2170140-50-6((R)-GSK-3685032)
Name GSK3685032 TFA
Synonyms GSK 3685032 TFA; GSK-3685032 TFA;
SMILES
Chemical Name
Formula C24H25F3N6O3S M. Wt 534.56
Purity 98% Storage Store at 4-8°C
Description GSK3685032 is a first-in-class potent, non-nucleoside, reversible, DNMT1-selective inhibitor (IC50: 0.17 µM), exerting robust DNA hypomethylation and gene activation, potently inhibiting growth of cancer cell lines, displaying improved tolerability and greater DNA hypomethylation than decitabine (DAC), translating into superior antitumour activity in models of AML.
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