Mometasone New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 105102-22-5 | Cat. No. | BCP45832 |
| Name | Mometasone | ||
| Synonyms | Mometasonum; | ||
| SMILES | CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CCl)O)C)O)Cl)C | ||
| Chemical Name | |||
| Formula | C22H28Cl2O4 | M. Wt | 427.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Mometasone is a synthetic topical glucocorticoid receptor (GR) agonist with anti-inflammatory, anti-pruritic and vasoconstrictive properties. Upon administration, mometasone binds to cytoplasmic GRs and subsequently activates GR-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators. Specifically, mometasone appears to induce phospholipase A2 inhibitory proteins, thereby controlling the release of the inflammatory precursor arachidonic acid from phospholipid membrane by phospholipase A2. | ||
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