SN-38 Glucuronide New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 121080-63-5 | Cat. No. | BCP24172 |
| Name | SN-38 Glucuronide | ||
| Synonyms | SN38 glucuronide;SN 38 glucuronide;SN-38G; | ||
| SMILES | CCC1=C2C=C(C=CC2=NC3=C1CN4C3=CC5=C(C4=O)COC(=O)C5(CC)O)OC6C(C(C(C(O6)C(=O)O)O)O)O | ||
| Chemical Name | |||
| Formula | C28H28N2O11 | M. Wt | 568.53 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SN38 glucuronide is a metabolite of irinotecan. Irinotecan is a drug used for the treatment of cancer. Irinotecan prevents DNA from unwinding by inhibition of topoisomerase 1. In chemical terms, it is a semisynthetic analogue of the natural alkaloid camptothecin. Its main use is in colon cancer, in particular, in combination with other chemotherapy agents. This includes the regimen FOLFIRI, which consists of infusional 5-fluorouracil, leucovorin, and irinotecan. Irinotecan received accelerated approval by the U. S. | ||
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