Seocalcitol New
Data Sheet
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| CAS No. | 134404-52-7 | Cat. No. | BCP38354 |
| Name | Seocalcitol | ||
| Synonyms | EB-1089;EB 1089;EB1089; | ||
| SMILES | CCC(CC)(C=CC=CC(C)C1CCC2C1(CCCC2=CC=C3CC(CC(C3=C)O)O)C)O | ||
| Chemical Name | |||
| Formula | C30H46O3 | M. Wt | 454.68 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Seocalcitol is a vitamin D3 analogue with potential antineoplastic activity. Seocalcitol binds to and activates the vitamin D receptor, a cytoplasmic polypeptide expressed in normal vitamin D responsive tissues, but also overexpressed in certain cancers including hepatocellular carcinoma and pancreatic cancer. Mediated through vitamin D receptor, this agent induces cancer cell differentiation, inhibits cancer cell growth and induces apoptosis. In addition, seocalcitol may also induce growth arrest and apoptosis independent of vitamin D receptor activation through mechanisms that are not fully elucidated. | ||
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