Inecalcitol New
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| CAS No. | 163217-09-2 | Cat. No. | BCP23832 |
| Name | Inecalcitol | ||
| Synonyms | TX-522; TX 522; TX522; | ||
| SMILES | CC(CC#CC(C)(C)O)C1CCC2C1(CCCC2=CC=C3CC(CC(C3)O)O)C | ||
| Chemical Name | |||
| Formula | C26H40O3 | M. Wt | 400.59 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Inecalcitol is an analog of calcitriol and a vitamin D3 receptor (VDR) agonist, with potential antineoplastic activity. Upon administration, inecalcitol targets and binds to VDR. This activates VDR and VDR-mediated signal transduction pathways. This modulates the VDR-mediated expression of certain genes, including the expression of anti-cancer genes, enhances cellular differentiation, induces tumor cell apoptosis and inhibits tumor cell growth. VDR plays a central role in calcium homeostasis and in the growth of certain cancer cells. | ||
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