CL 316243 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 138908-40-4 | Cat. No. | BCP44544 |
| Name | CL 316243 | ||
| Synonyms | CL 316243; CL316243; CL-316,243; CL 316,243; CL316,243. HP 186; HP-186; HP186; | ||
| SMILES | CC(CC1=CC2=C(C=C1)OC(O2)(C(=O)[O-])C(=O)[O-])NCC(C3=CC(=CC=C3)Cl)O.[Na+].[Na+] | ||
| Chemical Name | |||
| Formula | C20H18ClNO7.2Na | M. Wt | 465.79 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | CL-316243 is a potent and highly selective β3-adrenoceptor agonist (EC50 = 3 nM); > 10000-fold selective over β1 and β2 receptors. CL-316243 restores the expression of down-regulated fatty acid oxidation genes in type 2 diabetic mice. CL-316,243 enhances insulin-stimulated glucose disposal in nonobese rats. CL 316243 possesses anti-obesity and anti-diabetic effects and consequently may be useful for treating obesity as well as non-insulin-dependent diabetes mellitus in obese persons, without causing excessive side effects. | ||
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