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T-3775440 Chemical Structure

T-3775440

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30535CAS No. :1422620-34-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1422620-34-5 Cat. No. BCP30535
Name T-3775440
Synonyms T 3775440;T3775440;
SMILES CN1C=C(C=N1)C(=O)NC2=CC=C(C=C2)C3CC3NCC4CC4
Chemical Name
Formula C18H22N4O M. Wt 310.40
Purity 98% Storage Store at 4-8°C
Description T-3775440 is a novel potent, selecitve, irreversible LSD1 inhibitor with IC50 of 2.1 nM; displays high selectivity for LSD1 relative to other monoamine oxidases (e.g., MAO-A and MAO-B); disrupts the interaction between LSD1 and growth factor-independent 1B (GFI1B) in leukemia cell lines, exhibites significant antitumor efficacy in AEL and AMKL xenograft models.
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