LY2955303
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1433497-19-8 | Cat. No. | BCP20655 |
| Name | LY2955303 | ||
| Synonyms | LY-2955303; LY 2955303; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C36H42N4O3 | M. Wt | 578.74 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | LY2955303 is a potent and selective RAR-gamma antagonist for the treatment of osteoarthritis pain. LY2955303 has RAR-gamma Ki = 1.09 nM; RAR-alpha Ki > 1700 nM; RAR-beta Ki > 2980 nM. LY2955303 demonstrated good pharmacokinetic properties and was efficacious in the MIA model of osteoarthritis-like joint pain. LY2955303 demonstrated an improved margin to RAR -mediated adverse effects. | ||
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