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GLPG1837 Chemical Structure

GLPG1837

Cat. No. :BCP23611CAS No. :1654725-02-6Purity:98%
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Synonyms GLPG 1837; GLPG1837; ABBV-974; ABBV 974; ABBV974
CAS Number 1654725-02-6
Purity 98%
M. Wt 348.42
Formula C16H20N4O3S
Storage Store at 4-8°C
GLPG-1837, also known as ABBV-974, is a novel cystic fibrosis transmembrane conductance regulator (CFTR) potentiator1. GLPG1837 was generally safe and well tolerated in healthy subjects up to the highest dose of 800 mg twice daily for 2 weeks. GLPG1837 shows enhanced efficacy on CFTR mutants harboring Class III mutations compared to Ivacaftor, the first marketed potentiator.

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