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VX-661 Chemical Structure

VX-661

Cat. No. :BCP07173CAS No. :1152311-62-0Purity:98%
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Synonyms VX 661; VX661;Tezacaftor
CAS Number 1152311-62-0
Purity 98%
M. Wt 520.5
Formula C26H27F3N2O6
Storage Store at 4-8°C
VX-661 is CFTR modulator. VX-661 is potentially useful for treatment of cystic fibrosis disease. Cystic fibrosis (CF) is a genetic disease caused by defects in the CF transmembrane regulator (CFTR) gene, which encodes an epithelial chloride channel. The most common mutation, Δ508CFTR, produces a protein that is misfolded and does not reach the cell membrane. VX-661 can correct trafficking of Δ508CFTR and partially restore chloride channel activity.

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