NIK SMI1 New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1660114-31-7 | Cat. No. | BCP38023 |
| Name | NIK SMI1 | ||
| Synonyms | NIKSMI1; NIK-SMI1;NIK inhibitor 4f; | ||
| SMILES | CN1CCC(C1=O)(C#CC2=CC(=CC=C2)C3=NC(=CC(=C3)OC)C(=O)N)O | ||
| Chemical Name | |||
| Formula | C20H19N3O4 | M. Wt | 365.39 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | NIK SMI1 is a potent, selective small molecule inhibitor of NF-κB inducing kinase (NIK) with Ki of 230±170 pM; only inhibits 3 out of 222 off-target kinases (KHS1, LRRK2, and PKD1) with >75% inhibition at 1 uM; potently inhibits anti-LTβR-induced nuclear p52 levels in anti-LTβR-stimulated HeLa cells, with no effect on canonical signaling; inhibits BAFF and CD40 signaling, suppresses immune responses in vivo; suppresses disease biomarkers and improves survival and renal function in NZB/W F1 mice. | ||
Recommend Products
More >
-
-
Sodium salicylate
Cat. No.：BCP47031
No.：54-21-7
Product Details -
Sappanone A
Cat. No.：BCP46467
No.：102067-84-5
Product Details -
-
-
WAY-204688
Cat. No.：BCP46376
No.：796854-35-8
Product Details -
-
N-Acetyl-cysteine
Cat. No.：BCP45078
No.：616-91-1
Product Details -
-
-
Lipoteichoic acid
Cat. No.：BCP43680
No.：56411-57-5
Product Details -
-
-
-
-
-
Dihydrobigelovin
Cat. No.：BCP34452
No.：54999-07-4
Product Details -
-
-
Edasalonexent
Cat. No.：BCP25138
No.：1204317-86-1
Product Details
Tags:NIK SMI1 supplier,NIK SMI1 purchase,NIK SMI1 manufacturer,NIK SMI1 distributor,NIK SMI1 cost,NIK SMI1 buy,NIK SMI1 for sale