Fortunellin New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP39988CAS No. ：20633-93-6Purity：98%

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CAS No.	20633-93-6	Cat. No.	BCP39988
Name	Fortunellin
Synonyms	Acacetin-7-neohesperidoside;
SMILES	CC1C(C(C(C(O1)OC2C(C(C(OC2OC3=CC(=C4C(=C3)OC(=CC4=O)C5=CC=C(C=C5)OC)O)CO)O)O)O)O)O
Chemical Name
Formula	C28H32O14	M. Wt	592.55
Purity	98%	Storage	Store at 4-8°C
Description	Fortunellin is an antioxidant and anti-inflammatory agent that has been active against inflammation and oxidative stress that contribute to the progression of diabetic cardiomyopathy (DCM). Fortunellin may alleviate heart function and reduce inflammation and oxidative stress. The pro-inflammatory cytokines and the expression of p-IκB kinase α (IKKα), p-IκBα, and p-nuclear factor-κB (NF-κB) are inhibited by Fortunellin, while superoxide dismutase (SOD), catalase (CAT), heme oxygenase-1 (HO-1) and p-AMP-activated protein kinase (AMPK) were significantly enhanced. Fortunellin likely protects against fructose-induced inflammation and oxidative stress by enhancing AMPK/Nrf2 pathway in diabetic mice and cardiomyocytes with fructose treatment.