Diphyllin New
Data Sheet
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| CAS No. | 22055-22-7 | Cat. No. | BCP39987 |
| Name | Diphyllin | ||
| Synonyms | |||
| SMILES | COC1=C(C=C2C(=C1)C(=C3C(=C2O)COC3=O)C4=CC5=C(C=C4)OCO5)OC | ||
| Chemical Name | |||
| Formula | C21H16O7 | M. Wt | 380.35 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Diphyllin is an arylnaphthalene lignan isolated from Justicia procumbens and is a potent HIV-1 inhibitor with an IC50 of 0.38 μM. Diphyllin is active against vesicular stomatitis virus (VSV) and influenza virus. Diphyllin is a vacuolar type H+-ATPase (V-ATPase) inhibitor with an IC50 value of 17 nM and inhibits lysosomal acidification in human osteoclasts. Diphyllin inhibits NO production with an IC50 of 50 μM and has anticancer and anti-inflammatory activities. | ||
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