BAY-299 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2080306-23-4 | Cat. No. | BCP41584 |
| Name | BAY-299 | ||
| Synonyms | BAY 299; BAY299; | ||
| SMILES | CC1=CC2=C(C=C1N3C(=O)C4=C5C(=C(C=C4)CCCO)C=CC=C5C3=O)N(C(=O)N2C)C | ||
| Chemical Name | |||
| Formula | C25H23N3O4 | M. Wt | 429.47 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BAY 299 is a potent and selective inhibitor of BRD1 and TAF1 (IC50 = 6-67 and 8-13 nM, respectively) with selectivity over other bromodomains (>30-fold over other members of the BRPF family; BRD9 and ATAD2; >300-fold over BRD4). BAY 299 suppresses binding of BRD1 and TAF1 to histone H4 (IC50 = 575 nM and 0.9 μM, respectively) and histone H3.3 (IC50 = 825 nM and 1.4 μM, respectively). | ||
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