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MA-0204 Chemical Structure

MA-0204

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30365CAS No. :2095128-17-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2095128-17-7 Cat. No. BCP30365
Name MA-0204
Synonyms MA 0204; MA0204;
SMILES CC1=CN=C(N1CC2=CC=CC=C2OCCCC(C)CC(=O)O)C3=CC=C(C=C3)OC(F)(F)F
Chemical Name
Formula C25H27F3N2O4 M. Wt 476.49
Purity 98% Storage Store at 4-8°C
Description MA-0204 is a highly potent and selective PPARd modulator (PPARδ EC50 = 0.4 nM; PPARalpha, EC50 == 6,660 nM) that upregulates the expression of FAO genes in human renal proximal tubule cells, resulting in increased mitochondrial fatty acid oxidation. In normal rats undergoing IR-AKI, MA-0204 attenuates the increases of plasma and urinary biomarkers of AKI, improves renal function, mitigates proximal tubular damage and boosts mitochondrial gene expression.
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