Zotatifin New
Data Sheet
For research use only. Not for human use.
| Size | Price | Stock | Quotation Inquiry |
|---|---|---|---|
| 1.00 mg | Get quote | In-stock | Quotation Inquiry |
| 2.00 mg | Get quote | In-stock | Quotation Inquiry |
Get Quotation Now Tel: 0086-13026320035 or orders@biochempartner.com
Real-Time Inquiry ×
* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 2098191-53-6 | Cat. No. | BCP35487 |
| Name | Zotatifin | ||
| Synonyms | eFT226; eFT 226; eFT-226; | ||
| SMILES | CN(C)CC1C(C2(C(C1O)(C3=C(N=C(C=C3O2)OC)OC)O)C4=CC=C(C=C4)C#N)C5=CC=CC=C5 | ||
| Chemical Name | |||
| Formula | C28H29N3O5 | M. Wt | 487.56 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Zotatifin (eFT226) is a potent and selective inhibitor of eIF4A, is efficacious in preclinical models of lymphoma. eFT226 promotes eIF4A1 binding to specific 5’-UTR polypurine and/or G-quadraplex recognition motifs leading to a selective block in ribosome mRNA scanning. eFT226 shows potent anti-proliferative activity (GI50 < 15 nM) against a panel of B-cell lymphoma cell lines. Treatment with eFT226 leads to coordinated inhibition of MYC, CCND1/3, BCL2 or MCL1 protein expression resulting in significant anti-tumor activity. | ||
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.
Recommend Products
More >
Tags:Zotatifin supplier,Zotatifin purchase,Zotatifin manufacturer,Zotatifin distributor,Zotatifin cost,Zotatifin buy,Zotatifin for sale