Labetalol New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP31095CAS No. ：36894-69-6Purity：98%

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CAS No.	36894-69-6	Cat. No.	BCP31095
Name	Labetalol
Synonyms	Labetolol;Albetol;Normodyne;Apo-Labetalol;
SMILES	CC(CCC1=CC=CC=C1)NCC(C2=CC(=C(C=C2)O)C(=O)N)O
Chemical Name
Formula	C19H24N2O3	M. Wt	328.41
Purity	98%	Storage	Store at 4-8°C
Description	Labetalol is a third generation selective alpha-1-adrenergic antagonist and non-selective beta-adrenergic antagonist with vasodilatory and antihypertensive properties. Labetalol competitively binds to alpha-1-adrenergic receptors in vascular smooth muscle, thereby inhibiting the adrenergic stimulation of endothelial cell function and vasoconstriction in peripheral blood vessels. This agent also binds to beta-receptors in the bronchial and vascular smooth muscle, resulting in a decrease in adrenergic stimulation. The result is a decrease in resting and exercise heart rates, cardiac output, and in both systolic and diastolic blood pressure, thereby resulting in vasodilation, and negative chronotropic and inotropic cardiac effects.