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Pirfenidone Chemical Structure

Pirfenidone

Data Sheet For research use only. Not for human use.
Cat. No. :BCP04473CAS No. :53179-13-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 53179-13-8 Cat. No. BCP04473
Name Pirfenidone
Synonyms AMR69; AMR-69; AMR 69;
SMILES CC1=CN(C(=O)C=C1)C2=CC=CC=C2
Chemical Name
Formula C12H11NO M. Wt 185.22
Purity 98% Storage Store at 4-8°C
Description Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β.
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