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CAS No. | 6104-71-8 | Cat. No. | BCP30683 |
Name | N-Desmethylclozapine | ||
Synonyms | Norclozapine; Desmethylclozapine; Normethylclozapinee; ACP-104; ACP104; ACP 104; | ||
SMILES | C1CN(CCN1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42 | ||
Chemical Name | |||
Formula | C17H17ClN4 | M. Wt | 312.8 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Norclozapine is the major metabolite of Clozapine. Clozapine is an atypical antipsychotic medication used in the treatment of schizophrenia, and is also sometimes used off-label for the treatment of bipolar disorder. Clozapine is extensively metabolized in the liver, via the cytochrome P450 system, to polar metabolites suitable for elimination in the urine and feces. The major metabolite, norclozapine (desmethyl-clozapine), is pharmacologically active. |
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