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Delamanid Chemical Structure

Delamanid

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP07838CAS No. ：681492-22-8Purity：98%
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  • Publications Citing of Biochempartner's Delamanid
Antimicrob Agents Chemother. 2019 Aug; 63(8): e00031-19.
  • Chemical Properties&Biological Activity
CAS No. 681492-22-8 Cat. No. BCP07838
Name Delamanid
Synonyms OPC-67683; OPC 67683; OPC67683;
SMILES FC(F)(F)OC1=CC=C(OC2CCN(C3=CC=C(OC[C@@]4(C)CN5C(O4)=NC([N+]([O-])=O)=C5)C=C3)CC2)C=C1
Chemical Name
Formula C25H25F3N4O6 M. Wt 534.48
Purity 98% Storage Store at 4-8°C
Description Delamanid, also known as OPC-67683, is a drug for the treatment of multi-drug-resistant tuberculosis. It works by blocking the synthesis of mycolic acids in Mycobacterium tuberculosis, the organism which causes tuberculosis, thus destabilising its cell wall. The drug is approved in the EU. Delamanid inhibits the synthesis of mycolic acids, crucial component of the cell wall of the Mycobacterium tuberculosis complex. Delamanid is insoluble in water and its activity was proven in several in vitro and in vivo studies. Its bactericidal activity was demonstrated in individuals with drug-susceptible and drug-resistant tuberculosis (MDR- and XDR-TB).
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H-NMR HPLC
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