Aclarubicin Hydrochloride New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 75443-99-1 | Cat. No. | BCP07926 |
| Name | Aclarubicin Hydrochloride | ||
| Synonyms | Aclacinomycin A hydrochloride; Aclarubicin HCl; Antibiotic MA144A1;MA-144A1;MA144A1;MA 144A1; | ||
| SMILES | CCC1(CC(C2=C(C1C(=O)OC)C=C3C(=C2O)C(=O)C4=C(C3=O)C=CC=C4O)OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)OC7CCC(=O)C(O7)C)O)N(C)C)O.Cl | ||
| Chemical Name | |||
| Formula | C42H54ClNO15 | M. Wt | 848.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Aclarubicin hydrochloride is an anthracycline produced by Streptomyces galilaeus. Aclarubicin is an oligosaccharide anthracycline antineoplastic antibiotic isolated from the bacterium Streptomyces galilaeus. Aclarubicin intercalates into DNA and interacts with topoisomerases I and II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. Aclarubicin is antagonistic to other agents that inhibit topoisomerase II, such as etoposide, teniposide and amsacrine. This agent is less cardiotoxic than doxorubicin and daunorubicin. | ||
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