Cilastatin sodium
Data Sheet
For research use only. Not for human use.
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| CAS No. | 81129-83-1 | Cat. No. | BCP09574 |
| Name | Cilastatin sodium | ||
| Synonyms | Cilastatin; Cilastatine; Cilastatinum; MK 0791; MK 791; M K-791; MK0791; MK791; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C16H24N2Na2O5S | M. Wt | 402.42 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Cilastatin is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Dehydropeptidase is an enzyme found in the kidney and is responsible for degrading the antibiotic imipenem. Cilastatin can therefore be combined intravenously with imipenem in order to protect it from dehydropeptidase and prolong its antibacterial effect. Cilastatin itself does not have antibiotic activity although it has been proved to be active against a zinc-dependent beta-lactamase that usually confer antibiotic resistance to certain bacteria. | ||
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