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AF353 Chemical Structure

AF353

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP28391CAS No. ：865305-30-2Purity：98
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  • Chemical Properties&Biological Activity
CAS No. 865305-30-2 Cat. No. BCP28391
Name AF353
Synonyms AF-353; AF 353;Ro-4;
SMILES CC(C)C1=CC(=C(C=C1OC2=CN=C(N=C2N)N)I)OC
Chemical Name
Formula C14H17IN4O2 M. Wt 400.21
Purity 98 Storage Store at 4-8°C
Description AF353 is a P2X3 receptor antagonist. Antagonism of the P2X3 receptor is one of the potential therapeutic strategies for the management of neuropathic pain because P2X3 receptors are predominantly localized on small to medium diameter C- and Aδ-fiber primary afferent neurons, which are related to the pain-sensing system.
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