AT101
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 90141-22-3 | Cat. No. | BCP03607 |
| Name | AT101 | ||
| Synonyms | AT 101;AT-101; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C30H30O8 | M. Wt | 518.55 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | As a BH3 mimetic, AT-101 binds to the hydrophobic surface binding groove BH3 of the anti-apoptotic proteins Bcl-2 and Bcl-xL, blocking their heterodimerization with pro-apoptotic members of the Bcl-2 family of proteins such as Bad, Bid, and Bim; this may result in the inhibition of tumor cell proliferation and the induction of tumor cell apoptosis. AT-101 induces apoptosis in vitro through activation of caspase-9; cytotoxic to multiple myeloma and drug-resistant cell lines. AT-101 delays onset of androgen-independent growth of VCaP prostate cancer xenografts in vivo. | ||
Recommend Products
More >
-
BCL6-IN-3
Cat. No.：BCP49128
No.：2253878-44-1
Product Details -
(R)-MIK665
Cat. No.：BCP47788
No.：1799831-02-9
Product Details -
Lisaftoclax
Cat. No.：BCP47569
No.：2180923-05-9
Product Details -
-
-
-
-
-
-
BCL2 Degrader C5
Cat. No.：BCP36383
No.：2378801-85-3
Product Details -
Bcl-2-IN-2
Cat. No.：BCP36375
No.：2383085-86-5
Product Details -
Marinopyrrole A
Cat. No.：BCP36069
No.：1227962-62-0
Product Details -
-
(+)-Apogossypol
Cat. No.：BCP32267
No.：66389-74-0
Product Details -
-
AZD-5991 Racemate
Cat. No.：BCP23513
No.：2143010-83-5
Product Details -
-
-
-
Pyridoclax
Cat. No.：BCP23863
No.：1651890-44-6
Product Details
Tags:AT101 supplier,AT101 purchase,AT101 manufacturer,AT101 distributor,AT101 cost,AT101 buy,AT101 for sale