SJ10542 New
Data Sheet
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| CAS No. | SJ10542 | Cat. No. | BCP46974 |
| Name | SJ10542 | ||
| Synonyms | SJ 10542; SJ-10542; | ||
| SMILES | CCS(=O)(=O)N1CC(C1)(CC#N)N2C=C(C=N2)C3=C4C=CNC4=NC(=N3)NC5=CC=C(C=C5)C(=O)NCCCN6CCN(CC6)C7=CC=C(C=C7)C8CCC(=O)NC8=O | ||
| Chemical Name | |||
| Formula | C41H46N12O5S | M. Wt | 818.96 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SJ10542 is a potent and selective JAK2/3 directing phenyl glutarimide (PG)-PROTAC with DC50s of 14, 11, and 24 nM for JAK2, JAK3, and JAK2-fusion ALL, respectively. SJ10542 utilizes a PG ligand as the cereblon (CRBN) recruiter. | ||
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