Indirubin-3
Data Sheet
For research use only. Not for human use.
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| CAS No. | 160807-49-8 | Cat. No. | BCP14390 |
| Name | Indirubin-3 | ||
| Synonyms | Indirubin-3-monoxime;Indirubin-3-oxime; | ||
| SMILES | O=C1NC2=C(C=CC=C2)/C1=C3NC4=C(C=CC=C4)C\3=N/O | ||
| Chemical Name | |||
| Formula | C16H11N3O2 | M. Wt | 277.28 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Indirubin-3'-monoxime is a potent GSK-3β inhibitor, and a less potent inhibitor of 5-Lipoxygenase, with IC50s of 22 nM and 7.8-10 µM, respectively; also shows inhibitory activities against CDK5/p25 and CDK1/cyclin B, with IC50s of 100 and 180 nM. | ||
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