Nordihydroguaiaretic acid
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 500-38-9 | Cat. No. | BCP08590 |
| Name | Nordihydroguaiaretic acid | ||
| Synonyms | NDGA;Masoprocol; | ||
| SMILES | CC(CC1=CC=C(O)C(O)=C1)C(C)CC2=CC=C(O)C(O)=C2 | ||
| Chemical Name | |||
| Formula | C18H22O4 | M. Wt | 302.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Nordihydroguaiaretic acid, also known as NDGA, is a naturally occurring antioxidant dicatechol originally derived from the creosote bush Larrea divaricatta with antipromoter, anti-inflammatory, and antineoplastic activities. NDGA directly inhibits activation of two receptor tyrosine kinases (RTKs), the insulin-like growth factor receptor (IGF-1R) and the c-erbB2/HER2/neu receptor, resulting in decreased proliferation of susceptible tumor cell populations. This agent may induce apoptosis in susceptible tumor cell populations as a result of disruption of the actin cytoskeleton in association with the activation of stress activated protein kinases (SAPKs). In addition, NDGA inhibits arachidonic acid 5-lipoxygenase (5LOX), resulting in diminished synthesis of inflammatory mediators such as prostaglandins and leukotrines; it may prevent leukocyte infiltration into tissues and the release of reactive oxygen species and, at higher concentrations, may also inhibit cyclooxygenase. | ||
Recommend Products
More >
-
-
PXS5505 HCl
Cat. No.：BCP39659
No.：2409964-23-2
Product Details -
-
11-Keto-beta-boswellic acid
Cat. No.：BCP32934
No.：17019-92-0
Product Details -
-
-
-
-
Dehydroabietic acid
Cat. No.：BCP18786
No.：1740-19-8
Product Details -
Terameprocol
Cat. No.：BCP24515
No.：24150-24-1
Product Details -
-
-
Indirubin-3
Cat. No.：BCP14390
No.：160807-49-8
Product Details -
-
-
Tags:Nordihydroguaiaretic acid supplier,Nordihydroguaiaretic acid purchase,Nordihydroguaiaretic acid manufacturer,Nordihydroguaiaretic acid distributor,Nordihydroguaiaretic acid cost,Nordihydroguaiaretic acid buy,Nordihydroguaiaretic acid for sale