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Cabazitaxel Chemical Structure

Cabazitaxel

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP27641CAS No. ：183133-96-2Purity：98%
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  • Publications Citing of Biochempartner's Cabazitaxel
Drug Deliv Transl Res . 2022 Feb 19. April 2022Drug Delivery and Translational Research
Nanotheranostics. 2019; 3(1): 103–112. Drug Deliv Transl Res. 2022 Apr 15 : 1–18.
Transl Oncol. 2020 Aug; 13(8): 100793. Transl Oncol. 2020 Aug; 13(8): 100793.
  • Chemical Properties&Biological Activity
CAS No. 183133-96-2 Cat. No. BCP27641
Name Cabazitaxel
Synonyms XRP6258; XRP-6258; XRP 6258; TXD 258; TXD-258; TXD258;
SMILES
Chemical Name
Formula C45H57NO14 M. Wt 835.93
Purity 98% Storage Store at 4-8°C
Description Cabazitaxel increases CYP3A enzyme activities in rat hepatocytes. The mean ex-vivo human plasma protein binding of Cabazitaxel is 91.6%. Cabazitaxel is rapidly and extensively metabolised in numerous metabolites. Cabazitaxel demonstrates activity in several murine and human resistant cell lines.With a 4-day exposure to cabazitaxel, cytotoxicity is noted with relatively low cabazitaxel concentrations. Cabazitaxel shows high antitumor activity in 3 human colorectal cell lines (HCT-116, HCT-8, and HT-29).
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H-NMR HPLC
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