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Bilastine Chemical Structure

Bilastine

Cat. No. ：BCP02576CAS No. ：202189-78-4Purity：98%
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Synonyms Bilastinum;Ilaxten
CAS Number 202189-78-4
Purity 98%
M. Wt 463.61
Formula C28H37N3O3
Storage Store at 4-8°C
Bilastine binds to histamine H1-receptors as indicated by its displacement of [3H]-pyrilamine from H1-receptors expressed in guinea-pig cerebellum and human embryonic kidney (HEK) cell lines. The studies conducted on guinea-pig smooth muscle demonstrated the capability of bilastine to antagonise H1-receptors. Bilastine is selective for histamine H1-receptors as shown in receptor-binding screening conducted to determine the binding capacity of bilastine to 30 different receptors . Bilastine distribution has an apparent volume of distribution of 1.29 L/kg, and has an elimination half-life of 14.5 h and plasma protein binding of 84-90% .
LCMS H-NMR

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