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Bilastine Chemical Structure

Bilastine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP02576CAS No. :202189-78-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 202189-78-4 Cat. No. BCP02576
Name Bilastine
Synonyms Bilastinum;Ilaxten;
SMILES
Chemical Name
Formula C28H37N3O3 M. Wt 463.61
Purity 98% Storage Store at 4-8°C
Description Bilastine binds to histamine H1-receptors as indicated by its displacement of [3H]-pyrilamine from H1-receptors expressed in guinea-pig cerebellum and human embryonic kidney (HEK) cell lines. The studies conducted on guinea-pig smooth muscle demonstrated the capability of bilastine to antagonise H1-receptors. Bilastine is selective for histamine H1-receptors as shown in receptor-binding screening conducted to determine the binding capacity of bilastine to 30 different receptors . Bilastine distribution has an apparent volume of distribution of 1.29 L/kg, and has an elimination half-life of 14.5 h and plasma protein binding of 84-90% .
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