LY411575
Data Sheet
For research use only. Not for human use.
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| CAS No. | 209984-57-6 | Cat. No. | BCP02531 |
| Name | LY411575 | ||
| Synonyms | LY 411575;LY-411575; LSN-411575; LSN 411575; LSN411575; | ||
| SMILES | O=C1[C@@H](NC([C@@H](NC([C@](C2=CC(F)=CC(F)=C2)O)=O)C)=O)C3=CC=CC=C3C(C=CC=C4)=C4N1C | ||
| Chemical Name | |||
| Formula | C26H23F2N3O4 | M. Wt | 479.48 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | LY 411575, also known as LSN-411575, is potent, cell permeable and selective γ-secretase inhibitor that reduces Aβ/42 after acute or chronic treatment, and blocks Notch activation. The gamma secretase inhibitor, activating pPKC alpha intracellular pathway could be suggested to prevent or reduce downstream toxic events, representing a useful strategy to counteract Alzheimer's disease. | ||
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