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Thalidomide Chemical Structure

Thalidomide

Cat. No. :BCP19772CAS No. :50-35-1Purity:98%
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Synonyms Thalomid
CAS Number 50-35-1
Purity 98%
M. Wt 258.23
Formula C13H10N2O4
Storage Store at 4-8°C
Thalidomide is a synthetic derivative of glutamic acid (alpha-phthalimido-glutarimide) with teratogenic, immunomodulatory, anti-inflammatory and anti-angiogenic properties. Thalidomide acts primarily by inhibiting both the production of tumor necrosis factor alpha (TNF-alpha) in stimulated peripheral monocytes and the activities of interleukins and interferons. This agent also inhibits polymorphonuclear chemotaxis and monocyte phagocytosis. In addition, thalidomide inhibits pro-angiogenic factors such as vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (bFGF), thereby inhibiting angiogenesis.

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