Ulixertinib Discount

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP04232CAS No. ：869886-67-9Purity：98%

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CAS No.	869886-67-9	Cat. No.	BCP04232
Name	Ulixertinib
Synonyms	1956366-10-1; BVD-523; BVD 523; BVD523; VRT752271; VRT752271; VRT 752271;;
SMILES	O=C(C1=CC(C2=CC(NC(C)C)=NC=C2Cl)=CN1)N[C@@H](C3=CC=CC(Cl)=C3)CO
Chemical Name
Formula	C21H22Cl2N4O2	M. Wt	433.33
Purity	98%	Storage	Store at 4-8°C
Description	Ulixertinib, also known as BVD-523 and VRT752271, is an inhibitors of ERK protein kinase. Downmodulation of ERK protein kinase activity inhibits VEGF secretion by human myeloma cells and myeloma-induced angiogenesis. Upon oral administration, BVD-523 inhibits both ERK 1 and 2, thereby preventing the activation of ERK-mediated signal transduction pathways. This results in the inhibition of ERK-dependent tumor cell proliferation and survival. The mitogen-activated protein kinase (MAPK)/ERK pathway is often upregulated in a variety of tumor cell types and plays a key role in tumor cell proliferation, differentiation and survival.