G5-7 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 939681-36-4 | Cat. No. | BCP46781 |
| Name | G5-7 | ||
| Synonyms | JAK2 inhibitor G5-7; | ||
| SMILES | CC(C)(C)OC(=O)N1CC(=CC2=CC=CC=C2F)C(=O)C(=CC3=CC=CC=C3F)C1 | ||
| Chemical Name | |||
| Formula | C22H19F2NO3 | M. Wt | 383.39 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | G5-7, an orally active and allosteric JAK2 inhibitor, selectively inhibits JAK2 mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 induces cell cycle arrest, apoptosis and possesses antiangiogenic effect. | ||
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