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MLN0905 Chemical Structure

MLN0905

Data Sheet For research use only. Not for human use.
Cat. No. :BCP05348CAS No. :1228960-69-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1228960-69-7 Cat. No. BCP05348
Name MLN0905
Synonyms PLK1 Inhibitor;MLN 0905;MLN-0905;
SMILES
Chemical Name
Formula C24H25F3N6S M. Wt 486.56
Purity 98% Storage Store at 4-8°C
Description MLN0905 is a potent inhibitor of PLK1 with IC50 of 2 nM. MLN0905 inhibits cell mitosis with EC50 of 9 nM. MLN0905 inhibits Cdc25C-T96 phosphorylation, a direct readout of PLK1 inhibition with EC50 of 29 nM. MLN0905 inhibits HT-29 viability with LD50 of 22 nM. MLN0905 possesses reasonable selectivity against a panel of 359 kinases.MLN0905 inhibits a panel of lymphoma cells viability with IC50 of 3 – 24 nM.
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