MPI-5a
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1259296-46-2 | Cat. No. | BCP29593 |
| Name | MPI-5a | ||
| Synonyms | MPI 5a;MPI5a;HDAC6 Inhibitor;Histone Deacetylase 6; | ||
| SMILES | CN1C=CC=C1C(=O)N2CCC3=C(C2)C=CC(=C3)C(=O)NO | ||
| Chemical Name | |||
| Formula | C16H17N3O3 | M. Wt | 299.32 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | MPI-5a is a potent selective inhibitor of HDAC6, and poorly blocks other HDAC enzymes.HDAC6 is a predominantly cytoplasmic enzyme that targets α-tubulin, cortactin, and heat shock protein 90, as well as other substrates. In this way, it impacts development, proliferation, invasion, and tumorigenesis. HDAC6 Inhibitor is a potent and selective inhibitor of HDAC6 (IC50 = 36 nM) that poorly blocks other HDAC enzymes. It is cell permeable, inhibiting the acetylation of tubulin in cells with an IC50 value of 210 nM. | ||
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