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GNE7915 Chemical Structure

GNE7915

Data Sheet For research use only. Not for human use.
Cat. No. :BCP09873CAS No. :1351761-44-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1351761-44-8 Cat. No. BCP09873
Related Products 2070015-00-6(GNE7915 tosylate)
Name GNE7915
Synonyms GNE-7915;GNE7915;
SMILES CCNC1=NC(=NC=C1C(F)(F)F)NC2=C(C=C(C(=C2)F)C(=O)N3CCOCC3)OC
Chemical Name
Formula C19H21F4N5O3 M. Wt 443.4
Purity 98% Storage Store at 4-8°C
Description GNE-7915 is a potent LRRK2 kinase inhibitor, which possess an ideal balance of LRRK2 cellular potency, broad kinase selectivity, metabolic stability, and brain penetration across multiple species. GNE-7915 was reported as a potent (IC50=9 nM) selective (1/187 kinases), brain-penetrant and non-toxic inhibitor of LRRK2.
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