TP-064 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2080306-20-1 | Cat. No. | BCP43164 |
| Name | TP-064 | ||
| Synonyms | TP 064; TP064; | ||
| SMILES | CNCCN1CCC(CC1)C2=NC=CC(=C2)CN(C)C(=O)C3=CC(=CC=C3)OC4=CC=CC=C4 | ||
| Chemical Name | |||
| Formula | C28H34N4O2 | M. Wt | 458.6 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | TP-064 is a potent and selective PRMT4 inhibitor. The in vitro activity of TP-064 includes inhibition of PRMT4 with IC50 < 10nM for methylation of H3 (1-25) and greater than 100-fold selectivity over other histone methyltransferases and non-epigenetic targets. In cellular assays, TP-064 inhibits the methylation of MED12 with IC50 = 43 nM. | ||
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