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TPX-0131 Chemical Structure

TPX-0131

Data Sheet For research use only. Not for human use.
Cat. No. :BCP42131CAS No. :2648641-36-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2648641-36-3 Cat. No. BCP42131
Name TPX-0131
Synonyms TPX0131;TPX 0131;
SMILES CC1(COC2=C(CN3C(COC4=CN5C(=C(C=N5)C(=O)N1)N=C43)C(F)F)C=C(C=C2)F)C
Chemical Name
Formula C21H20F3N5O3 M. Wt 447.41
Purity 98% Storage Store at 4-8°C
Description TPX-0131 is a CNS-penetrant, next-generation ALK inhibitor that has potency against wild-type ALK and a spectrum of acquired resistance mutations, especially the G1202R solvent front mutation and compound mutations, for which there are currently no effective therapies.
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