ZX-29 New
Data Sheet
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| CAS No. | 2254805-62-2 | Cat. No. | BCP45485 |
| Name | ZX-29 | ||
| Synonyms | ZX 29;ZX29; | ||
| SMILES | CS(=O)(NC1=CC=CC=C1NC2=NC(NC3=CC=C(N4CCN(C)CC4)C=C3OC)=NC=C2Cl)=O | ||
| Chemical Name | |||
| Formula | C23H28ClN7O3S | M. Wt | 518.03 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ZX-29 is a potent and selective ALK inhibitor for ALK, ALK L1196M and ALK G1202R mutations, respectively. ZX-29 is inactive against EGFR. ZX-29 induces apoptosis by inducing endoplasmic reticulum (ER) stress and overcomes cell resistance caused by an ALK mutation. ZX-29 also induces protective autophagy and has antitumor effect. | ||
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