Alectinib Hydrochloride New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1256589-74-8 | Cat. No. | BCP09075 |
| Related Products | 1256580-46-7（Alectinib） | ||
| Name | Alectinib Hydrochloride | ||
| Synonyms | CH-5428402 HCl; AF-802 Hydrochloride; RG-7853 Hydrochloride; RO-5424802 Hydrochloride; | ||
| SMILES | [H]Cl.N#CC1=CC2=C(C3=C(N2)C(C)(C4=CC(N5CCC(CC5)N6CCOCC6)=C(C=C4C3=O)CC)C)C=C1 | ||
| Chemical Name | |||
| Formula | C30H35ClN4O2 | M. Wt | 519.08 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Alectinib Hydrochloride (CH5424802 Hydrochloride; RO5424802 Hydrochloride; AF-802 Hydrochloride) is a potent, selective, and orally available ALK inhibitor with IC50 of 1.9 nM, the dissociation constant (KD) value for ALK in an ATP-competitive manner is 2.4 nM using a competition-bind assay.Alectinib, also known as AF802, or CH5424802 or RO5424802, is a potent, selective, and orally available ALK inhibitor with a unique chemical scaffold, showing preferential antitumor activity against cancers with gene alterations of ALK, such as nonsmall cell lung cancer (NSCLC) cells expressing EML4-ALK fusion and anaplastic large-cell lymphoma (ALCL) cells expressing NPM-ALK fusion in vitro and in vivo. Alectinib inhibited ALK L1196M, which corresponds to the gatekeeper mutation conferring common resistance to kinase inhibitors, and blocked EML4-ALK L1196M-driven cell growth. | ||
Recommend Products
More >
-
-
-
-
-
-
-
SAR348830
Cat. No.：BCP31069
No.：1462949-64-9
Product Details -
-
-
BIO-013077-01
Cat. No.：BCP30129
No.：746667-48-1
Product Details -
Belizatinib
Cat. No.：BCP29521
No.：1357920-84-3
Product Details -
Ensartinib dihydrochloride
Cat. No.：BCP29059
No.：2137030-98-7
Product Details -
LDN-193189 2HCl
Cat. No.：BCP20431
No.：1435934-00-1
Product Details -
-
HG-14-10-04
Cat. No.：BCP24835
No.：1356962-34-9
Product Details -
CEP-28122 monomesilate hydrochloride salt
Cat. No.：BCP24832
No.：1354545-57-5
Product Details -
KRCA-0008
Cat. No.：BCP16229
No.：1472795-20-2
Product Details -
CEP-28122
Cat. No.：BCP15177
No.：1022958-60-6
Product Details -
-
ALK inhibitor 1
Cat. No.：BCP28167
No.：761436-81-1
Product Details
Tags:Alectinib Hydrochloride supplier,Alectinib Hydrochloride purchase,Alectinib Hydrochloride manufacturer,Alectinib Hydrochloride distributor,Alectinib Hydrochloride cost,Alectinib Hydrochloride buy,Alectinib Hydrochloride for sale