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Pifithrin-β hydrobromide Chemical Structure

Pifithrin-β hydrobromide

Cat. No. :BCP17578CAS No. :511296-88-1Purity:98%
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Synonyms Cyclic Pifithrin-α hydrobromide; Cyclic PFT-α hydrobromide; PFT-β hydrobromide; QB 102; QB-102; QB102
CAS Number 511296-88-1
Purity 98%
M. Wt 349.29
Formula C16H16N2S.HBr
Storage Store at 4-8°C
Pifithrin-β is a cyclic analog of pifithrin-α, a small molecule inhibitor of p53. Prevents dexamethasone-induced cell death in murine thymocytes (EC50 = 2.01 μM). Sensitizes p53-deficient tumors to radiotherapy and chemotherapy; increases apoptosis in target cells when used in combination with antimicrotubule agents.

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