Trifluridine
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 70-00-8 | Cat. No. | BCP09147 |
| Related Products | 733030-01-8（Trifluridine-tipiracil hydrochloride mixture） | ||
| Name | Trifluridine | ||
| Synonyms | FTD;Viroptic;Trifluorothymidine;NSC 529182;NSC 75520;NSC-75520; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C10H11F3N2O5 | M. Wt | 296.2 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: When HeLa cells were treated with TFT at a concentration of 1 uM (IC50 value), the concentration of TFT in the DNA was calculated as 62.2±0.9 pmol/1x106 cells for 4 h. Unlike FdUrd and 5FU, TFT resulted in an earlier phosphorylation of ATR and chk1 proteins after only 24 h of exposure, while phosphorylated ATM, BRCA2 and chk2 proteins were detected after more than 48 h of exposure to TFT . SN38 and TFT induced most DNA damage in H630 and Colo320 cells, which was increased in combination. TFT pre-incubation further enhanced SN38-induced DNA strand breaks in H630 and Colo320 (>20%), which was most pronounced in H630 cells (p<0.01) . in vivo: After oral administration of TFT in rats, more than 75% of the TFT was absorbed . | ||
Recommend Products
More >
-
Fluorodeoxyuridylate
Cat. No.：BCP31154
No.：134-46-3
Product Details -
Capecitabine
Cat. No.：BCP29814
No.：158798-73-3
Product Details -
Spongouridine
Cat. No.：BCP29295
No.：3083-77-0
Product Details -
CNDAC HCl salt
Cat. No.：BCP19489
No.：134665-72-8
Product Details -
-
-
-
-
-
Doxifluridine
Cat. No.：BCP12582
No.：3094-09-5
Product Details -
MeriMepodib
Cat. No.：BCP28336
No.：198821-22-6
Product Details -
-
-
-
-
Nelarabine
Cat. No.：BCP02093
No.：121032-29-9
Product Details -
Clofarabine
Cat. No.：BCP23422
No.：123318-82-1
Product Details -
-
Gemcitabine Monophosphate
Cat. No.：BCP21656
No.：116371-67-6
Product Details -
Tipiracil HCl
Cat. No.：BCP06245
No.：183204-72-0
Product Details
Tags:Trifluridine supplier,Trifluridine purchase,Trifluridine manufacturer,Trifluridine distributor,Trifluridine cost,Trifluridine buy,Trifluridine for sale