GSK180736A New
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| CAS No. | 817194-38-0 | Cat. No. | BCP25022 |
| Name | GSK180736A | ||
| Synonyms | GSK-180736A; GSK 180736A; | ||
| SMILES | CC1=C(C(NC(=O)N1)C2=CC=C(C=C2)F)C(=O)NC3=CC4=C(C=C3)NN=C4 | ||
| Chemical Name | |||
| Formula | C19H16FN5O2 | M. Wt | 365.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GSK180736A is potent and selective inhibitor of GRK2 with an IC50 of 0.77 μM25 and >100-fold selectivity over other GRKs. It is a weak inhibitor of PKA with an IC50 of 30 μM, but highly potent against ROCK1 (IC50 = 100 nM). | ||
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