H-1152 Dihydrochloride Chemical Structure

H-1152 Dihydrochloride New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP25257CAS No. ：871543-07-6Purity：98%

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Chemical Properties&Biological Activity

CAS No.	871543-07-6	Cat. No.	BCP25257
Name	H-1152 Dihydrochloride
Synonyms	H-1152 2HCl; H1152 dihydrochloride;
SMILES	CC1CNCCCN1S(=O)(=O)C2=CC=CC3=C2C(=CN=C3)C.Cl.Cl
Chemical Name
Formula	C16H23Cl2N3O2S	M. Wt	392.34
Purity	98%	Storage	Store at 4-8°C
Description	H 1152 dihydrochloride is a rho-kinase (ROCK) inhibitor that displays high selectivity over other protein kinases (IC50 values are 0.012, 0.180, 0.360, 0.745, 3.03, 5.68 and 28.3 μM for ROCKII, CAMKII, PKG, Aurora A, PKA, PKC and MLCK respectively). Inhibits sulprostone-induced contractions in guinea pig aorta (IC50 = 190 nM) and displays proerectile effects in rats.

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