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Glycyl-H 1152 dihydrochloride Chemical Structure

Glycyl-H 1152 dihydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP27782CAS No. :913844-45-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 913844-45-8 Cat. No. BCP27782
Name Glycyl-H 1152 dihydrochloride
Synonyms H-1152Glycyl, Dihydrochloride; Rho Kinase Inhibitor IV;
SMILES CC1CN(CCCN1S(=O)(=O)C2=CC=CC3=C2C(=CN=C3)C)C(=O)CN.Cl.Cl
Chemical Name
Formula C18H24N4O3S.2HCl M. Wt 449.4
Purity 98% Storage Store at 4-8°C
Description Glycyl-H 1152 dihydrochloride is a glycyl analog of the Rho-kinase inhibitor H 1152 dihydrochloride with an improved selectivity for ROCKII (IC50 = 0.0118, 2.35, 2.57, 3.26, > 10 and >10 μM for ROCKII, Aurora A, CAMKII, PKG, PKA and PKC, respectively). Glycyl-H 1152 dihydrochloride is used for the treatment of hypertension and arteriosclerosis.
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