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IκB/IKK

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IκB/IKK

Chemical Structure Cat. No. Product Name CAS No.
WS3 Chemical Structure
 BCP10968 WS3 1421227-52-2
WS3 is a novel small molecule that promotes β cell proliferation with EC50 of 28 nM(induced R7T1 proliferation).
Acetyl-trans-resveratrol Chemical Structure
 BCP24098 Acetyl-trans-resveratrol 42206-94-0
Triacetyl resveratrol is Resveratrol prodrug.
Wedelolactone Chemical Structure
 BCP19859 Wedelolactone 524-12-9
Wedelolactone is an inhibitor of IKK.
Bay 11-7821 Chemical Structure
 BCP06798 Bay 11-7821 19542-67-7
BAY 11-7082 is a NF-κB inhibitor which decreases NF-κB by inhibiting TNF-α-induced phosphorylation of IκB-α. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 with IC50s of 0.19 μM and 0.96 μM, respectively.
IKK epsilon-IN-1 Chemical Structure
 BCP10993 IKK epsilon-IN-1 1292310-49-6
MDK10496, also known as IKKε-IN-1, is a potent IKK inhibitor.
AZD3264 Chemical Structure
 BCP23957 AZD3264 1609281-86-8
AZD3264 is a novel Inhibitor of IkB-kinase IKK2.
PS-1145 Chemical Structure
 BCP24095 PS-1145 431898-65-6
PS-1145 is an IκB kinase (IKK) inhibitor with an IC50 of 88 nM.
SC514 Chemical Structure
 BCP21098 SC514 354812-17-2
SC514 is a selective IKK-2 inhibitor (IC50=11.2±4.7 μM), which does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.
IKK-16 HCl Chemical Structure
 BCP08242 IKK-16 HCl 1186195-62-9
IKK 16 is a selective IκB kinase (IKK) inhibitor.
IKK16 Chemical Structure
 BCP19060 IKK16 873225-46-8
IKK 16 is a selective IκB kinase (IKK) inhibitor for IKK2, IKK complex and IKK1 with IC50s of 40 nM, 70 nM and 200 nM, respectively. IKK16 also inhibits leucine-rich repeat kinase-2 (LRRK2) with an IC50 of 50 nM.
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