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Amyloid β

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Amyloid β

Chemical Structure Cat. No. Product Name CAS No.
CGP 52411 Chemical Structure
 BCP27630 CGP 52411 145915-58-8
CGP 52411, also called DAPH, inhibits and reverses the formation of Aβ42 fibers (β-sheet content of aggregated β-amyloid (1-42): IC50 = 4.5 µM) in neurons associated with Alzheimer's disease.
EUK-134 Chemical Structure
 BCP08133 EUK-134 81065-76-1
EUK 134, a synthetic superoxide dismutase (SOD)/catalase mimetic, exhibits potent antioxidant activities, and inhibits the formation of β-amyloid and related amyloid fibril.
Aducanumab Chemical Structure
 BCP24776 Aducanumab 1384260-65-4
Aducanumab targets aggregated forms of β-amyloid (Aβ) in the hopes of reducing its buildup.
Florbetaben F-18 Chemical Structure
 BCP12850 Florbetaben F-18 902143-01-5
Florbetaben f-18 is a Radioactive Diagnostic Agent. The mechanism of action of florbetaben f-18 is as a Positron Emitting Activity.
Gamma-Secretase Modulators Chemical Structure
 BCP12943 Gamma-Secretase Modulators 937812-80-1
Gamma-Secretase Modulators (Amyloid-β production inhibitor) is a Amyloid-β production inhibitor. Gamma-Secretase Modulators is useful for Alzheimer's disease.
Aftin-4 Chemical Structure
 BCP29117 Aftin-4 866893-90-5
Aftin-4 is an Amyloid-β42 (Aβ42) inducer.
GSK3039294 Chemical Structure
 BCP23653 GSK3039294 1819986-22-5
GS3039294 is a Serum amyloid P component inhibitor.
Notoginsenoside R1 Chemical Structure
 BCP14046 Notoginsenoside R1 80418-24-2
Notoginsenoside R1, the main bioactive component in panaxnotoginseng, is reported have some neuronal protective, antihypertensive effects.
HOECHST 34580 Chemical Structure
 BCP20754 HOECHST 34580 23555-00-2
Hoechst 34580 is a cell-permeable fluorescent dye for staining DNA and nuclei.
Semagacestat Chemical Structure
 BCP01878 Semagacestat 425386-60-3
Semagacestat (LY450139) is a γ-secretase blocker with an IC50 of 15 nM.
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