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NF κB

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NF κB

Chemical Structure Cat. No. Product Name CAS No.
UCB-9260 Chemical Structure
 BCP40717 UCB-9260 1515888-53-5
UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer.
NIK SMI1 Chemical Structure
 BCP38023 NIK SMI1 1660114-31-7
NIK SMI1 is a highly selective and potent NF-κB-inducing kinase (NIK) inhibitor.
SEMBL Chemical Structure
 BCP38022 SEMBL 1443448-82-5
SEMBL is a potent NF-κB inhibitor that inhibits DNA binding of NF-κB component p65.
Urolithin B Chemical Structure
 BCP35736 Urolithin B 1139-83-9
Urolithin B belongs to the class of organic compounds known as coumarins and derivatives. These are polycyclic aromatic compounds containing a 1-benzopyran moiety with a ketone group at the C2 carbon atom (1-benzopyran-2-one). Urolithin b is considered to be a practically insoluble (in water) and relatively neutral molecule.
DHMEQ Chemical Structure
 BCP35164 DHMEQ 287194-40-5
DHMEQ is a potent NF-κB inhibitor.
Dihydrobigelovin Chemical Structure
 BCP34452 Dihydrobigelovin 54999-07-4
Ergolide is a sesquiterpene lactone isolated from the dried flowers of Inula Britannica. Ergolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation of NF-κB.
Tyrosol Chemical Structure
 BCP34277 Tyrosol 501-94-0
Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.
DCZ0415 Chemical Structure
 BCP33607 DCZ0415 2242470-43-3
DCZ0415 is a novel inhibitor of TRIP13, suppressing multiple myeloma progression.
11-Keto-beta-boswellic acid Chemical Structure
 BCP32934 11-Keto-beta-boswellic acid 17019-92-0
11-Keto-beta-boswellic acid is a pentacyclic triterpenic acid of the oleogum resin from the bark of the Boswellia serrate tree, popularly known as Indian Frankincense.
Methylthiouracil Chemical Structure
 BCP21374 Methylthiouracil 56-04-2
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
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