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NF κB

Chemical Structure Cat. No. Product Name CAS No.
Methylthiouracil Chemical Structure
 BCP21374 Methylthiouracil 56-04-2
Methylthiouracil is an antithyroid agent. Methylthiouracil suppresses the production TNF-α and IL-6, and the activation of NF-κB and ERK1/2.
Shikonin Chemical Structure
 BCP29329 Shikonin 517-89-5
Shikonin is a major component of a Chinese herbal medicine named zicao. Shikonin has shown various biological activities, including inhibition of TNF-α, NF-κB, HIV-1.
Eleutheroside E Chemical Structure
 BCP15731 Eleutheroside E 39432-56-9
Eleutheroside E has anti-inflammatory effect by inhibiting NF-κB activities.
Ginsenoside-Rg5 Chemical Structure
 BCP10278 Ginsenoside-Rg5 186763-78-0
Ginsenoside Rg5 is a triterpenoid saponin. It has a role as a metabolite.
Rocaglamide Chemical Structure
 BCP30539 Rocaglamide 84573-16-0
Rocaglamide is a potent NF-κB activation inhibitor.
H-ALA-ALA-VAL-ALA-LEU-LEU-PRO-ALA-VAL-LEU-LEU-ALA-LEU-LEU-ALA-PRO-VAL-GLN-ARG-LYS-ARG-GLN-LYS-LEU-MET-PRO-OH Chemical Structure
 BCP30335 H-ALA-ALA-VAL-ALA-LEU-LEU-PRO-ALA-VAL-LEU-LEU-ALA-LEU-LEU-ALA-PRO-VAL-GLN-ARG-LYS-ARG-GLN-LYS-LEU-MET-PRO-OH 213546-53-3
SN50 is a cell permeable inhibitor of NF-κB translocation.
DL-Thioctic acid Chemical Structure
 BCP13221 DL-Thioctic acid 1077-28-7
Alpha-Lipoic Acid is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation.
Naringin Dihydrochalcone Chemical Structure
 BCP27691 Naringin Dihydrochalcone 18916-17-1
Naringin Dihydrochalcone(Naringin DC) is a new-style sweetening agent and an artificial sweetener derived from naringin and also an inhibitor of CYP enzymes.
Andrographolide Chemical Structure
 BCP28277 Andrographolide 5508-58-7
Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation.
CBL0137 Chemical Structure
 BCP29977 CBL0137 1197996-80-7
CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 μM and inhibits NF-κB with an EC50 of 0.47 μM.
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