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NF κB

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NF κB

Chemical Structure Cat. No. Product Name CAS No.
Andrographolide Chemical Structure
BCP28277 Andrographolide 5508-58-7
Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation.
CBL0137 Chemical Structure
BCP29977 CBL0137 1197996-80-7
CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 μM and inhibits NF-κB with an EC50 of 0.47 μM.
Prostratin Chemical Structure
BCP29895 Prostratin 60857-08-1
Prostratin is a protein kinase C activator. Inhibits growth and induces differentiation of AML cell lines.
DTP3 Chemical Structure
BCP23603 DTP3 DTP3
DTP3 is an inhibitor of GADD45β/MKK7 complex.
ALKS-8700 Chemical Structure
BCP20867 ALKS-8700 1577222-14-0
Diroximel fumarate, also known as ALKS-8700, is a prodrug of monomethyl fumarate in a controlled-release formulation that rapidly and efficiently converts to MMF in the body.
Cynaropicrin Chemical Structure
BCP15633 Cynaropicrin 35730-78-0
Cynaropicrin is a sesquiterpene lactone which can inhibit tumor necrosis factor (TNF-α) release with IC50s of 8.24 and 3.18 μM for murine and human macrophage cells, respectively.
Schisantherin A Chemical Structure
BCP15178 Schisantherin A 58546-56-8
Schisantherin A is a dibenzocyclooctadiene lignan isolated from the fruit of Schisandra sphenanthera. Schisantherin A inhibits p65-NF-κB translocation into the nucleus by IκBα degradation.
Erdosteine Chemical Structure
BCP07677 Erdosteine 84611-23-4
Erdosteine is a mucolytic which is used in treatment of excessive viscous mucus.
Ginsenoside Rd Chemical Structure
BCP11505 Ginsenoside Rd 52705-93-8
Ginsenoside Rd inhibits TNFα-induced NF-κB transcriptional activity with an IC50 of 12.05±0.82 μM in HepG2 cells.
Morusin Chemical Structure
BCP16494 Morusin 62596-29-6
Morusin is a prenylated flavonoid isolated from M.
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